Ameer Abdullah player props odds, tips and betting trends for Week 16

Watch Ameer Abdullah and the Colts vs. 49ers on Fubo!

Ameer Abdullah week 16 player props

• Time: 8:15 p.m. ET
• Date: December 22, 2025

National Football League odds courtesy of BetMGM. Odds updated Monday at 6:13 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Ameer Abdullah rushing stats and trends

• Abdullah’s average rushing yards over/under for the season is 12.5 yards, a figure he’s come up short of by an average of 6.6 yards.
• He has a rushing touchdown in one game this year.

Colts vs. 49ers stats and trends

• In terms of defending against the run, the 49ers are 12th in the NFL, allowing 106.1 yards per game.
• This week Abdullah will face the NFL’s 23rd-ranked pass defense (227.6 yards allowed per game).
• The Colts own the 11th-ranked passing offense this year (229.0 passing yards per game), and they’ve been less effective on the other side of the ball, ranking third-worst with 247.6 passing yards allowed per game.
• The Colts have been making things happen on both sides of the ball in the running game this season, as they rank fifth-best in rushing offense (128.9 rushing yards per game) and fourth-best in rushing defense (95.1 rushing yards allowed per game).
• The Colts rank 13th in yards per play allowed this year (5.5), but they’ve been thriving on offense, ranking third-best in the NFL with 6.2 yards per play.